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Seesmic, the maker of applications that monitor social networks across mobile devices, has announced a $4 million investment from salesforce.com, inc. and a Softbank Group company managed by Softbank Holdings Inc.

Salesforce.com, the enterprise cloud computing company, and Softbank Group join previous investors Atomico, Omidyar Network and Wellington Partners. Seesmic has received a total of $16 million, including the most-recent investment round.

Seesmic and salesforce.com have worked closely for more than six months to create a seamless integration between Seesmic Desktop and Salesforce Chatter, the industry’s first enterprise social collaboration app and platform.

Leveraging the social features popularized by Facebook and Twitter — such as profiles, status updates and real-time feeds — Chatter lets employees “follow” documents, people, business processes and application data. The result is a new level of productivity that crosses departments and organizational barriers.

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